Today we’d like to introduce you to Michael Ambrose.
Michael, we appreciate you taking the time to share your story with us today. Where does your story begin?
Dr. Michael Ambrose, MD, DC, MS, is a board-certified internal medicine physician and chiropractor who grew up in the Metro East area of Illinois. He began his career as a chiropractor after graduating from Logan College of Chiropractic in St. Louis, then returned to medical school to expand his training in internal medicine. Over the past decade, he has focused on researching and developing physician-led systems to deliver cutting-edge, personalized care that helps patients live longer, feel better, and “optimize their performance.”
Dr. Ambrose founded Performance Medical Clinic in Edwardsville, Illinois, with a mission to move beyond traditional “sick care” and instead provide proactive, integrative, performance based healthcare. The clinic specializes in hormone optimization for men and women, medical weight loss, and longevity medicine- using bioidentical hormone therapy, advanced peptide protocols, personalized weight-management programs, and longevity approaches to maximize both lifespan and healthspan.
Building on its success and growing demand for medically supervised optimization and longevity care, Performance Medical Clinic has now begun franchising. In August 2025, the company announced nationwide franchise opportunities, offering a turnkey, physician-owned model so qualified healthcare professionals and wellness-focused entrepreneurs can bring Performance Medical Clinic’s hormone therapy, medical weight loss, and longevity programs to communities across the United States.
Alright, so let’s dig a little deeper into the story – has it been an easy path overall and if not, what were the challenges you’ve had to overcome?
Despite Performance Medical Clinic’s growth, the journey hasn’t been without obstacles. One of the biggest unfortunate realities has been a crowded marketplace filled with newer spa-like clinics that are not physician-founded or medically led. Many are driven by sales teams and profit-focused operators who prioritize volume over patient safety, outcomes, and ethics. This has created confusion for patients and lowered industry standards- making it even more important for Performance Medical Clinic to stand apart through integrity, medical oversight, and evidence-based care. Instead of cutting corners or chasing trends, we’ve committed to raising the bar and proving that true medical expertise, patient trust, and long-term results will always win over money-driven shortcuts.
Great, so let’s talk business. Can you tell our readers more about what you do and what you think sets you apart from others?
What Sets Performance Medical Clinic Apart
1. Physician-Led From the Ground Up
Unlike many hormone therapy or weight-loss centers run by non-clinical owners, Performance Medical Clinic was founded, built and is actively guided by Dr. Michael Ambrose, a dual-trained MD and DC with advanced expertise in internal medicine, hormone optimization, medical weight loss, and longevity science.
This foundation ensures every protocol, treatment plan, and franchise model is grounded in real clinical evidence- not trends, fads, or sales-driven decisions.
2. A True Medical Model- Not a Spa Model
We offer:
Diagnostic-based treatment plans, Comprehensive lab work and biomarker tracking, Personalized hormone optimization, Advanced metabolic and longevity protocols
This elevates our services far beyond the “cookie-cutter” or one-size-fits-all programs commonly found in aesthetics or wellness franchises.
3. Proven, Reproducible Systems for Hormones, Weight Loss & Longevity
Dr. Ambrose has spent years developing repeatable, outcomes-driven systems for:
Hormone therapy for men and women
Medical weight loss programs
Peptide therapy
Longevity & performance medicine
These systems are designed so clinics in any market can deliver the same high level of patient success, safety, and satisfaction.
4. Focus on Optimization, Not Illness
While traditional medicine treats sickness, we operate on a different philosophy:
Optimize first, prevent decline, and extend healthspan.
This approach resonates with today’s consumers who want energy, confidence, strength, mental clarity, and long-term vitality- not just “normal labs.”
5. Franchise Support Based on Real Clinic Experience
We aren’t a corporate franchisor guessing what clinicians need.
Performance Medical Clinic is a functioning, profitable medical practice whose systems have been tested, refined, and proven in real patient care.
Our franchise model offers:
Clinical training and certification
Streamlined workflow systems
Marketing proven to convert
Ongoing medical and business support
A turnkey start-up pathway for rapid launch and scalability
Franchisees get a model created by a physician for physicians and healthcare entrepreneurs- not a diluted version created for mass-market franchising.
6. A Brand Built on Trust, Outcomes & Longevity Medicine
We stand out because we deliver measurable results and foster long-term patient relationships.
Performance Medical isn’t a trendy brand- it’s a medical movement focused on:
Regaining health
Preventing disease
Enhancing longevity
Improving quality of life
That purpose resonates deeply with patients and fuels long-term growth and loyalty.
7. Positioned at the Fastest-Growing Intersection in Healthcare
Hormone optimization, medical weight management, and longevity medicine are three of the fastest-expanding sectors in modern healthcare.
Performance Medical Clinic sits directly at the intersection of all three, which gives our brand durability and future-proof scalability that few competitors can match.
Where we are in life is often partly because of others. Who/what else deserves credit for how your story turned out?
Laura Ambrose: The Operational Backbone Behind Performance Medical Clinic
As Chief Operating Officer of Performance Medical Clinic, Laura Ambrose has been instrumental in transforming Dr. Michael Ambrose’s clinical vision into a scalable, efficient, and highly successful business model. While Dr. Ambrose leads the medical innovation and clinical direction, Laura ensures the organization functions with precision, consistency, and a focus on growth.
1. Turning Vision Into Systems
Training systems for both clinical and administrative staff
Workflows that ensure seamless patient care and exceptional service
Internal processes that make scaling possible
These systems are the reason Performance Medical Clinic isn’t just a great medical practice- it’s a reproducible model ready for national expansion.
2. Leading the Patient Experience
One of the clinic’s biggest differentiators is its elevated patient experience, and much of that is due to Laura’s leadership.
She ensures that:
Every patient interaction reflects the brand’s values
Staff are trained to deliver high-touch, concierge-level service
Communication, scheduling, and follow-ups run smoothly
The environment feels warm, welcoming, and streamlined
Her attention to detail is a major reason patients stay, refer others, and trust the brand.
3. Building a High-Performance Team
Laura has played a central role in hiring, training, and developing the clinic’s staff.
Identifying talent that aligns with the mission
Creating positive team culture
Ensuring every team member knows their role, responsibilities, and standards
Her leadership has created a team that consistently delivers excellence.
Contact Info:
- Website: https://performancemedicalclinic.com/
- Instagram: https://www.instagram.com/performancemedicalclinic/
- Facebook: https://www.facebook.com/performancemedicalclinic
- Youtube: https://www.youtube.com/channel/UC47qrP5jBRWXXyTHipIXJ_Q
- Other: https://google.com/maps/place/Performance+Medical+Clinic/@38.5765458,-89.9842236,15z/data=!4m5!3m4!1s0x0:0xb395ce401fec92a0!8m2!3d38.5765458!4d-89.9842236?shorturl=1
